KFU. Card publication. Syphilis epidemiology in 1994-2013, molecular epidemiological strain typing and determination of macrolide resistance in Treponema pallidum in 2013-2014 in Tuva Republic, Russia

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SYPHILIS EPIDEMIOLOGY IN 1994-2013, MOLECULAR EPIDEMIOLOGICAL STRAIN TYPING AND DETERMINATION OF MACROLIDE RESISTANCE IN TREPONEMA PALLIDUM IN 2013-2014 IN TUVA REPUBLIC, RUSSIA

Form of presentation

Articles in international journals and collections

Year of publication

2016

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Authors, employees of KFU

Khayrullin Rafil Fidailevich, author

Bibliographic description in the original language

Khairullin R, Vorobyev D, Obukhov A, Kuular U-H, Kubanova A, Kubanov A, Unemo M. Syphilis epidemiology in 1994-2013, molecular epidemiological strain typing and determination of macrolide resistance in Treponema pallidum in 2013-2014 in Tuva Republic, Russia. APMIS 2016.

Annotation

The incidence of syphilis in the Tuva Republic (geographical centre of Asia), Russia has been exceedingly high historically. No detailed examinations and no molecular investigations of Treponema pallidum strains transmitted in the Tuva Republic, or in general, in Russia, were published internationally. We examined the syphilis epidemiology in 1994?2013, and the molecular epidemiology and macrolide resistance in T. pallidum strains in 2013?2014 in the Tuva Republic. Among 95 mainly primary or secondary syphilis patients, the arp, tpr, tp0548 and 23S rRNA genes in 85 polA gene-positive genital ulcer specimens were characterized. The syphilis incidence in Tuva Republic peaked in 1998 (1562), however declined to 177 in 2013. Among the 70 (82%) completely genotyped specimens, six molecular strain types were found. Strain type 14d/f accounted for 91%, but also 14c/f, 14d/g, 14b/f, 14i/f, 9d/f, and 4d/f were identified. Two (2.4%) specimens contained the 23S rRNA A2058G macrolide resistance m

Keywords

Syphilis epidemiology, antimicrobial resistance, strain typing, sexual transmitted disease

The name of the journal

APMIS

URL

http://onlinelibrary.wiley.com/doi/10.1111/apm.12541/abstract

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=130581&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Khayrullin Rafil Fidailevich	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Khairullin R, Vorobyev D, Obukhov A, Kuular U-H, Kubanova A, Kubanov A, Unemo M. Syphilis epidemiology in 1994-2013, molecular epidemiological strain typing and determination of macrolide resistance in Treponema pallidum in 2013-2014 in Tuva Republic, Russia. APMIS 2016.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=130581&p_lang=2	ru_RU
dc.description.abstract	APMIS	ru_RU
dc.description.abstract	The incidence of syphilis in the Tuva Republic (geographical centre of Asia), Russia has been exceedingly high historically. No detailed examinations and no molecular investigations of Treponema pallidum strains transmitted in the Tuva Republic, or in general, in Russia, were published internationally. We examined the syphilis epidemiology in 1994?2013, and the molecular epidemiology and macrolide resistance in T. pallidum strains in 2013?2014 in the Tuva Republic. Among 95 mainly primary or secondary syphilis patients, the arp, tpr, tp0548 and 23S rRNA genes in 85 polA gene-positive genital ulcer specimens were characterized. The syphilis incidence in Tuva Republic peaked in 1998 (1562), however declined to 177 in 2013. Among the 70 (82%) completely genotyped specimens, six molecular strain types were found. Strain type 14d/f accounted for 91%, but also 14c/f, 14d/g, 14b/f, 14i/f, 9d/f, and 4d/f were identified. Two (2.4%) specimens contained the 23S rRNA A2058G macrolide resistance m	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Syphilis epidemiology	ru_RU
dc.subject	antimicrobial resistance	ru_RU
dc.subject	strain typing	ru_RU
dc.subject	sexual transmitted disease	ru_RU
dc.title	Syphilis epidemiology in 1994-2013, molecular epidemiological strain typing and determination of macrolide resistance in Treponema pallidum in 2013-2014 in Tuva Republic, Russia	ru_RU
dc.type	Articles in international journals and collections	ru_RU