KFU. Card publication. Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells

KAZAN
FEDERAL UNIVERSITY

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- 中文
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DYSBIOSIS OF CULTIVABLE AEROBIC MICROBIOTA TIGHTLY ASSOCIATED WITH COLON CANCER EPITHELIAL CELLS

Form of presentation

Articles in international journals and collections

Year of publication

2015

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Authors, employees of KFU

Zelenikhin Pavel Valerevich, author

Ilinskaya Olga Nikolaevna, author

Sokolova Evgeniya Aleksandrovna, author

Authors, postgraduates KFU

Nguen Tkhi Nga, postgraduate kfu

Bibliographic description in the original language

Siraj Y. Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells / Y. Siraj, N. Nguen, P. Zelenikhin, E. Sokolova, I. Gataullin, O. Ilinskaya // RJPBCS.- 2015.- V.6.- P.1658-1663.

Annotation

Modern researches focus on metagenome, metatranscriptome, and metaproteome of microorganisms associated with the incidence of colorectal cancer (CRC). Based on assays of fecal samples, it is difficult to obtain unambiguous conclusion about contribution of certain microorganisms to CRC. Bacteria tightly associated with colon mucosa could provide more data into CRC mechanisms and give a basis of future approaches for microbiota modulation and new therapies development. Here we characterize aerobic cultivable bacteria isolated from biopsy samples of human neoplastic and normal colon epithelia, to compare the spectrum and some physiological features of bacterial habitants of the biological niche, which nearby parts differ on a level of oncogenic transformation. 98 cultured bacterial strains from 28 patients with CRC were isolated, cultivated and identified using MALDI-TOF mass spectrometry. From colon biopsies cultivable Escherichia coli, Serratia marcescens and representatives of the gene

Keywords

colorectal cancer, microflora, antibiotic susceptibility, secreted RNase activity

The name of the journal

Research Journal of Pharmaceutical, Biological and Chemical Sciences

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=118548&p_lang=2

Resource files

File name	Size (MB)	Format
_235_.pdf	0,67	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Zelenikhin Pavel Valerevich	ru_RU
dc.contributor.author	Ilinskaya Olga Nikolaevna	ru_RU
dc.contributor.author	Sokolova Evgeniya Aleksandrovna	ru_RU
dc.contributor.author	Nguen Tkhi Nga	ru_RU
dc.date.accessioned	2015-01-01T00:00:00Z	ru_RU
dc.date.available	2015-01-01T00:00:00Z	ru_RU
dc.date.issued	2015	ru_RU
dc.identifier.citation	Siraj Y. Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells / Y. Siraj, N. Nguen, P. Zelenikhin, E. Sokolova, I. Gataullin, O. Ilinskaya // RJPBCS.- 2015.- V.6.- P.1658-1663.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=118548&p_lang=2	ru_RU
dc.description.abstract	Research Journal of Pharmaceutical, Biological and Chemical Sciences	ru_RU
dc.description.abstract	Modern researches focus on metagenome, metatranscriptome, and metaproteome of microorganisms associated with the incidence of colorectal cancer (CRC). Based on assays of fecal samples, it is difficult to obtain unambiguous conclusion about contribution of certain microorganisms to CRC. Bacteria tightly associated with colon mucosa could provide more data into CRC mechanisms and give a basis of future approaches for microbiota modulation and new therapies development. Here we characterize aerobic cultivable bacteria isolated from biopsy samples of human neoplastic and normal colon epithelia, to compare the spectrum and some physiological features of bacterial habitants of the biological niche, which nearby parts differ on a level of oncogenic transformation. 98 cultured bacterial strains from 28 patients with CRC were isolated, cultivated and identified using MALDI-TOF mass spectrometry. From colon biopsies cultivable Escherichia coli, Serratia marcescens and representatives of the gene	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	colorectal cancer	ru_RU
dc.subject	microflora	ru_RU
dc.subject	antibiotic susceptibility	ru_RU
dc.subject	secreted RNase activity	ru_RU
dc.title	Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells	ru_RU
dc.type	Articles in international journals and collections	ru_RU