KFU. Card publication. Numerical simulation of rheological, chemical and hydromechanical processes of thrombolysis

KAZAN
FEDERAL UNIVERSITY

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NUMERICAL SIMULATION OF RHEOLOGICAL, CHEMICAL AND HYDROMECHANICAL PROCESSES OF THROMBOLYSIS

Form of presentation

Articles in international journals and collections

Year of publication

2015

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Authors, employees of KFU

Khramchenkov Maksim Georgievich, author

Khramchenkov Eduard Maksimovich, author

Bibliographic description in the original language

Khramchenkov E. M. Numerical simulation of rheological, chemical and hydromechanical processes of thrombolysis / E.M. Khramchenkov, M.G. Khramchenkov // Journal of Physics: Conference Series, Volume 602, Issue 1, 15 April 2015, Article number 012042

Annotation

The aim of this work was to build a complex 3D-model of rheological, hydro- and chemical processes in deformable clot. The clot lysis like an example of such kind processes with regard of peculiarities of clot structure, such as porous media with elastic and elastic-viscous rheology, was analyzed. Fibrin of the clot is considered as stationary solid phase, plasminogen, plasmin and plasminogen-activators are considered as dissolved fluid phases. On the basis of obtained model we developed numerical solution to investigate processes which take place during thrombolysis, and investigated dynamics of thrombolysis, transport of components in fluid phase (blood plasma) and in solid phase (thrombus material) and influence of thrombus characteristics on the lysis. Obtained results show good correlation with works of predecessors and demonstrate significant influence of rheological properties of clot (fibrin) on the process of lysis. It's shown that the bigger elasticity increases rate of a clo

Keywords

clot, lysis, mathematical model

The name of the journal

Journal of Physics: Conference Series

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=112574&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Khramchenkov Maksim Georgievich	ru_RU
dc.contributor.author	Khramchenkov Eduard Maksimovich	ru_RU
dc.date.accessioned	2015-01-01T00:00:00Z	ru_RU
dc.date.available	2015-01-01T00:00:00Z	ru_RU
dc.date.issued	2015	ru_RU
dc.identifier.citation	Khramchenkov E. M. Numerical simulation of rheological, chemical and hydromechanical processes of thrombolysis / E.M. Khramchenkov, M.G. Khramchenkov // Journal of Physics: Conference Series, Volume 602, Issue 1, 15 April 2015, Article number 012042	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=112574&p_lang=2	ru_RU
dc.description.abstract	Journal of Physics: Conference Series	ru_RU
dc.description.abstract	The aim of this work was to build a complex 3D-model of rheological, hydro- and chemical processes in deformable clot. The clot lysis like an example of such kind processes with regard of peculiarities of clot structure, such as porous media with elastic and elastic-viscous rheology, was analyzed. Fibrin of the clot is considered as stationary solid phase, plasminogen, plasmin and plasminogen-activators are considered as dissolved fluid phases. On the basis of obtained model we developed numerical solution to investigate processes which take place during thrombolysis, and investigated dynamics of thrombolysis, transport of components in fluid phase (blood plasma) and in solid phase (thrombus material) and influence of thrombus characteristics on the lysis. Obtained results show good correlation with works of predecessors and demonstrate significant influence of rheological properties of clot (fibrin) on the process of lysis. It's shown that the bigger elasticity increases rate of a clo	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	clot	ru_RU
dc.subject	lysis	ru_RU
dc.subject	mathematical model	ru_RU
dc.title	Numerical simulation of rheological, chemical and hydromechanical processes of thrombolysis	ru_RU
dc.type	Articles in international journals and collections	ru_RU