Positions
Performance
Professional development
Performance
2023
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Титов Е.А. Четвертичные фосфониевые соли, содержащие фрагменты жирных кислот и терпеноидов: синтез и свойства/ Титов Е.А., Немтарев А.В., Паширова Т.Н., Миронов В.Ф// Сборник избранных тезисов Итоговой научно-практической конференции профессорско-преподавательского состава института физики и Химического института им. А.М. Бутлерова Казанского федерального университета - Казань, 2023 - С. 141
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Мухаметгалиева А.Р. Аномальное кинетическое поведение ацетилхолинэстеразы с бензоилхолином в качестве субстрата / Мухаметгалиева А.Р., Немтарев А.В., Сякаев В.В., Паширова Т.Н., Массон П. // ТЕЗИСЫ ДОКЛАДОВ
13-ой Международной научной конференции
«БИОКАТАЛИЗ. ФУНДАМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ
И ПРИМЕНЕНИЯ» (БИОКАТАЛИЗ - 2023). -
2023. - С. 199.
- Coccolini, C.DABCO-functionalized nanoemulsions with antimicrobial properties for potential treatment of ocular myasthenia gravis / C. Coccolini , E. Berselli , F. Fathi, M.B.P.P Oliveira , P. Masson, A.V. Bogdanov, T. Pashirova, K. Krambeck, E.B. Souto, Med. Sci. Forum, 2023, 2.
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Tsepaeva OV, Nemtarev AV, Pashirova TN, Novel triphenylphosphonium amphiphilic conjugates of glycerolipid type: synthesis, cytotoxic and antibacterial activity, and targeted cancer cell delivery//RSC MEDICINAL CHEMISTRY. - 2023. - Vol., Is.. - .
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Pashirova T.N, Shaihutdinova Z.M, Mironov V.F, Biomedical Nanosystems for In Vivo Detoxification: From Passive Delivery Systems to Functional Nanodevices and Nanorobots//Acta Naturae. - 2023. - Vol.15, Is.1-56. - P.4-12.
2022
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Pashirova T. Enzyme Nanoreactor for In Vivo Detoxification of Organophosphates / T.N. Pashirova, Z.Shaihutdinova, M. Mansurova M., R. Kazakova, D. Shambazova, A. Bogdanov, D. Tatarinov, D. Daudé, P. Jacquet, E. Chabrière, P. Masson // ACS Appl Mater Interfaces. - 2022. - 14(17). - 19241-19252.
F_proof.pdf -
174 Pashirova T.N., Shaihutdinova Z.M., Vandyukov A.E., Lyubina A.P., Amerhanova S.K., Voloshina A.D., Samorodov A.V., Souto E.B., Mironov V.F., Bogdanov A.V. Synthesis and structure-activity-toxicity relationships of DABCO-containing ammonium amphiphiles based on natural isatin scaffold // Journal of Molecular Liquids. – 2022. – Vol. 365. Art. 120217
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Pashirova T.N, Afonso A.B, Terekhova N.V, Nanogels for drug delivery: physicochemical properties, biological behavior, and in vivo applications//Nanotechnology and Regenerative Medicine: History, Techniques, Frontiers, and Applications. - 2022. - Vol., Is.. - P.95-131.
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Shajhutdinova Z, Pashirova T, Masson P., Kinetic Processes in Enzymatic Nanoreactors for In Vivo Detoxification//Biomedicines. - 2022. - Vol.10, Is.4. - Art. №784.
2021
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Rational Design 2-Hydroxypropylphosphonium Salts as Cancer Cell Mitochondria-Targeted Vectors: Synthesis, Structure, and Biological Properties / Mironov V.F., Nemtarev A.V., Tsepaeva O.V., Dimukhametov M.N., Litvinov I.A., Voloshina A.D., Pashirova T.N., Titov E.A., Lyubina A.P.,
Amerhanova S.K., Gubaidullin A.T., Islamov D.R. // Molecules. MDPI AG - 2021. - V. 26, N. 21, P. 6350
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Pashirova T.N, Bogdanov A, Masson P., Therapeutic nanoreactors for detoxification of xenobiotics: Concepts, challenges and biotechnological trends with special emphasis to organophosphate bioscavenging//Chemico-Biological Interactions. - 2021. - Vol.346, - P. 109577.
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Pashirova T.N., Fernandes A.R., Sanchez-Lopez E., Garcia M.L., Silva A.M., Zakharova L.Ya., Souto E.B., Chapter 5 - Polymer nanogels: Fabrication, structural behavior, and biological applications, in Theory and Applications of Nonparenteral Nanomedicines, Academic Press, 2021, Pages 97-111. doi: https://doi.org/10.1016/B978-0-12-820466-5.00005-3
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Bjerk T.R. Biosurfactants: Properties and Applications in Drug Delivery, Biotechnology and Ecotoxicology / T.R Bjerk, P. Severino, S. Jain, C. Marques, A.M. Silva, T. Pashirova, E.B. Souto // Bioengineering (Basel). - 2021 - 8(8). - P. 115.
bioengineering_08_00115_v2.pdf -
Титов Е.А. Оксираны в синтезе биологически активных 2-гидроксифосфониевых солей / Титов Е.А, Немтарев А.В., Паширова Т.Н., Миронов В.Ф. // Сборник IV Всероссийской с международной участием школы-конференции студентов, аспирантов и молодых ученых «Материалы и технологии XXI века« - Казань, 2021 - С. 153
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Pashirova T.N., Fernandes A.R., Sanchez-Lopez E., Garcia M.L., Silva A.M., Zakharova L.Ya., Souto E.B., Polymer nanogels: Fabrication, structural behavior, and biological applications, in Theory and Applications of Nonparenteral Nanomedicines, Eds. P. Kesharwani, S. Taurin, K. Greish, 2021, Elsevier, 97-111
978_0_12_820466_5.pdf
2020
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Burilova E.A, Pashirova T.N, Zueva I.V, Bi-functional sterically hindered phenol lipid-based delivery systems as potential multi-target agents against Alzheimer's disease via an intranasal route//Nanoscale. - 2020. - Vol.12, Is.25. - P.13757-13770.
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Terekhova N.V, Tatarinov D.A, Shaihutdinova Z.M, Design and synthesis of amphiphilic 2-hydroxybenzylphosphonium salts with antimicrobial and antitumor dual action//Bioorganic and Medicinal Chemistry Letters. - 2020. - Vol.30, Is.13. - Art. № 127234.
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Pashirova T.N., Fetin P.A., Lezov A.A., Kadnikov M.V., Valeeva F.G., Burilova E.A., Bilibin A.Yu., Zorin I.M., Self‐Assembled Quaternary Ammonium‐Containing Comb‐Like Polyelectrolytes for the Hydrolysis of Organophosphorous Esters: Effect of Head Groups and Counter‐Ions, ChemPlusChem, 2020, 85, 8, 1939-1948.
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Daina N Buzyurova, Tatiana N Pashirova, Irina V Zueva, Evgenia A Burilova, Zukhra M Shaihutdinova, Ildar Kh Rizvanov, Vasily M Babaev, Konstantin A Petrov, Eliana B Souto, Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: Pharmacokinetics in rat, Toxicology
. 2020, 444. 152578
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Pashirova T.N. Synthesis, structure-activity relationship and biological evaluation of tetracationic gemini Dabco-surfactants for transdermal liposomal formulations / Pashirova T.N. Sapunova A.S., Lukashenko S.S., Burilova E.A., Lubina A.P., Shaihutdinova Z.M., Gerasimova T.P., Kovalenko V.I., Voloshina A.D., Souto E.B., Zakharova L.Ya // Int J Pharm - 2020 - Vol. 575. - P. 118953
2019
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Zueva I, Dias J, Lushchekina S, New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease//Neuropharmacology. - 2019. - Vol.155, Is.. - P.131-141.
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Pashirova T.N., Burilova E.A., Tagasheva R.G., Zueva I.V., Gibadullina E.M., Nizameev I.R., Sudakov I.A., Vyshtakalyuk A.B., Voloshina A.D., Kadirov M.K., Petrov K.A., Burilov A.R., Bukharov S.V., Zakharova L.Y., Delivery nanosystems based on sterically hindered phenol derivatives containing a quaternary ammonium moiety: Synthesis, cholinesterase inhibition and antioxidant activity, Chem. Biol. Interact. 2019, 310, 108753.
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Silva A.M., Martins-Gomes C., Coutinho T.E., Fangueiro J.F., Sanchez-Lopez E., Pashirova T.N., Andreani T., Souto E.B., Soft cationic nanoparticles for drug delivery: production and cytotoxicity of solid lipid nanoparticles (SLNs), Applied sciences basel., 2019. 9(20), 4438.
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Pashirova T.N., Bogdanov A.V., Zaripova I.F., Burilova E.A., Vandyukov A.E., Sapunova A.S., Vandyukova I.I., Voloshina A.D., Mironov V.F., Zakharova L.Ya., Tunable amphiphilic π-systems based on isatin derivatives containing a quaternary ammonium moiety: The role of alkyl chain length in biological activity, J. Mol. Liq. 2019, 290, 111220.
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Pashirova T.N., Burilova E.A., Lukashenko S.S., Gaysin N.K., Gnezdilov O.I., Sapunova A.S., Fernandes A.R., Voloshina A.D., Souto E.B., Zhiltsova E.P., Zakharova L.Ya., Nontoxic antimicrobial micellar systems based on mono- and dicationic Dabco-surfactants and furazolidone: Structure-solubilization properties relationships, J. Mol. Liq., 2019, 112062
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Pashirova T.N., Zhukova N.A., Lukashenko S.S., Valeeva F.G., Burilova E.A., Sapunova A.S., Voloshina A.D., Mirgorodskaya A.B., Zakharova L.Y., Sinyashin O.G., Mamedov V.A., Multi-targeted approach by 2-benzimidazolylquinoxalines-loaded cationic arginine liposomes against сervical cancer cells in vitro, Colloids Surf. B Biointerfaces. 2019, 178, 317-328.
2018
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Zhiltsova E.P, Pashirova T.N, Ibatullina M.R, A new surfactant-copper(ii) complex based on 1,4-diazabicyclo[2.2.2]octane amphiphile. Crystal structure determination, self-assembly and functional activity//Physical Chemistry Chemical Physics. - 2018. - Vol.20, Is.18. - P.12688-12699.
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Burilova E.A, Pashirova T.N, Lukashenko S.S, Synthesis, biological evaluation and structure-activity relationships of self-assembled and solubilization properties of amphiphilic quaternary ammonium derivatives of quinuclidine//Journal of Molecular Liquids. - 2018. - Vol.272, Is.. - P.722-730.
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Pashirova T.N, Zueva I.V, Petrov K.A, Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model//Colloids and Surfaces B: Biointerfaces. - 2018. - Vol.171, Is.. - P.358-367.
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Pashirova T.N, Bra?ki A, Zueva I.V, Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection//Journal of Controlled Release. - 2018. - Vol.290, Is.. - P.102-111.
2017
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Pashirova T.N, Zueva I.V, Petrov K.A, Nanoparticle-Delivered 2-PAM for Rat Brain Protection against Paraoxon Central Toxicity//ACS Applied Materials and Interfaces. - 2017. - Vol.9, Is.20. - P.16922-16932.
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Pashirova T.N., Burilova E.A., Lukashenko S.S., Lenina O.A., Zobov V.V., Khamatgalimov, A.R., Kovalenko, V.I., Zakharova L.Y., Sinyashin O.G., Synthesis, Self-Association, and solubilizing ability of an amphiphilic derivative of poly(ethylene glycol) methyl ether, Rus. J. Gen. Chem., 2017, 87(12), 2832-2837.
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Pashirova T.N., Bogdanov A.V., Musin, L.I., Voronina J.K., Nizameev I.R., Kadirov M.K., Mironov V.F., Zakharova L.Ya., Latypov S.K., Sinyashin O.G., Nanoscale isoindigo-carriers: self-assembly and tunable properties, Beilstein J. Nanotechnol., 2017, 8, 313-324.
- Zhiltsova E. P., Ibatullina M. R., Lukashenko S. S., Complexes of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with transition metal nitrates. Micelle-forming, solubilizing, and adsorption properties//COLLOID JOURNAL. - 2017. - Vol.79, Is.5. - P.621-629.
2016
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Pashirova T.N., Andreani T., Macedo A.S., Souto E.B., Zakharova L.Ya., Development of gel-core solid lipid nanoparticles as drug delivery systems for hydrophilic molecules, Current Nanoscience, 2016, Vol. 12, №5, P. 598-604.
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Zhil'tsova E.P, Ibatullina M.R, Lukashenko S.S, Complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide: structure, aggregation, and biological activity//Russian Chemical Bulletin. - 2016. - Vol.65, Is.5. - P.1365-1371.
2015
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Pashirova T.N., Lukashenko S.S., Zakharov S.V., Voloshina A.D., Zhiltsova E.P., Zobov V.V., Souto E.B., Zakharova L.Ya., Self-assembling systems based on quaternized derivatives of 1,4-diazabicyclo[2.2.2]octane in nutrient broth as antimicrobial agents and carriers for hydrophobic drugs, Coll. Surf. B Biointerfaces, 2015, 127, 266–273.
- Zhil'tsova E. P., Ibatullina M. R., Lukashenko S. S., COMPLEXATION OF 1-ALKYL-4-AZA-1-AZONIABICYCLO[2.2.2] OCTANE BROMIDES WITH TRANSITION METAL CATIONS IN ACETONE//LIQUID CRYSTALS AND THEIR APPLICATION. - 2015. - Vol.15, Is.4. - P.48-55.
2012
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