Positions
Performance
2021
2020
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Mirgayazova R, Khadiullina R, Chasov V, Mingaleeva R, Miftakhova R, Rizvanov A, Bulatov E. Therapeutic editing of the TP53 gene: Is CRISPR/Cas9 an option?//Genes. - 2020. - Vol.11, Is.6. - P.1-17.
- Chasov V. Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy / V. Chasov, R. Mirgayazova, E. Zmievskaya, R. Khadiullina, A. Valiullina, J. S. Clarke, A. Rizvanov, M. G. J. Baud, E. Bulatov // Frontiers in oncology. - 2020. - V. 10. - A. 1460.
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Chasov V. Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy / V. Chasov, R. Mirgayazova, E. Zmievskaya, R. Khadiullina,
A. Valiullina, J. S. Clarke, A. Rizvanov, M. G. J. Baud, E. Bulatov // Frontiers in oncology. - 2020. - V. 10. - A. 1460.
F_fonc_10_01460.pdf
2019
- Regina Sayarova, Raniya Nazyrova, Rimma Mingaleeva, Olga Kartseva, Irina Glagoleva, Natalya Alexandrova, Azzam Hamad, Razan Subani, Vitaly Chasov, Rafil Khairullin, Regina Miftakhova, Matthias Baud, Albert Rizvanov, Emil Bulatov. Selective small molecule stabilisers/activators of p53(Y220C) mutant // CELL DEATH DISCOVERY. - 2019. - Vol.5.
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Mirgayazova R, Khadiullina R, Mingaleeva R, Chasov V, Gomzikova M, Garanina E, Rizvanov A, Bulatov E. Novel Isatin-based activator of p53 transcriptional functions in tumor cells//Molecular Biology Research Communications. - 2019. - Vol.8, Is.3. - P.119-128.
F_1_Published_MBRC53211568403000.pdf -
Valiullina A.KH. Evaluating CAR-T cells efficiency against solid tumors models / A. KH. Valiullina, R.M. Sayarova, E.A. Zmievskaya, M.O. Gomzikova, M.N. Zhuravleva, A.V. Petikhov, E.R. Bulatov, A.A. Rizvanov // ESGCT 27th Annual congress. - 2019. - P144.
F_P144_AbstractBook.pdf -
Mirgayazova R.M. Small molecule modulators of mutant p53 demonstrate selective cytotoxicity toward p53-Y220C cell lines / R.M. Mirgayazova, R.R. Khadiullina, R.N. Mingleeva, V.V. Chasov, M. Baud, A.A. Rizvanov, E.R. Bulatov // The international conference «The regulation of proteostasis in cancer« - 2019. - P. 53.
F_Tezisy.pdf -
Mingaleeva R. Expression of mutant p53 affects cancer cell sensitivity to topotecan / R. Mingaleeva, A. Sagdeeva, R. Sayarova, E. Bulatov, R.R. Miftakhova, A.A Rizvanov // Annals of Oncology. - 2019. - V. 30. - S. 5. - P. 2003
F_mdz269.021.pdf - Khadiullina R.R. Restoring impaired functions of mutant tumor supressor p53 using synthetic modulators / R.R. Khadiullina, R.M. Mirgayazova, R.N. Mingleeva, V.V. Chasov, M. Baud, A.A. Rizvanov, E.R. Bulatov // The international conference «The regulation of proteostasis in cancer«/ - 2019. - P. 24.
2018
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Bulatov E, Zagidullin A, Valiullina A, Sayarova R, Rizvanov A. Small molecule modulators of RING-type E3 ligases: MDM and cullin families as targets//Frontiers in Pharmacology. - 2018. - Vol.9, Is.MAY. - Art. № 450.
1_MDM_CRL_Review_Published.pdf -
Bulatov E, Valiullina A, Sayarova R, Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases//Immunology Letters. - 2018. - Vol.202, Is.. - P.44-51.
2018_Bulatov_ImmunoLetters.pdf -
Emil Bulatov, Regina Sayarova, Rimma Mingaleeva, Regina Miftakhova, Marina Gomzikova, Yuri Ignatyev, Alexey Petukhov, Pavel Davidovich, Albert Rizvanov & Nickolai A. Barlev. Isatin-Schiff base-copper (II) complex induces cell death in p53-positive tumor. Cell Death Discovery, Volume 4, Article number: 103 (2018)
1_Bulatov_CDDisco.pdf - Valiullina A. Evaluating efficacy of anti-CD19 CAR-T cells against CD19-positive 2D and 3D solid tumor models / A. Valiullina, R. Sayarova, M. Zhuravleva, S. Kletukhina, A. Petukhov, E. Bulatov, A. Rizvanov // Abstract book «Kazan precision medicine workshop», Kazan. - September 10-12, 2018. - P. 43.
- Aygul Valiullina, Regina Sayarova, Alexey Petukhov, Margarita Zhuravleva, Emil Bulatov, Albert Rizvanov. Anti-CD19 CAR-T cells are efficient against CD19-positive 3D bioprinted solid tumor models // HUMAN GENE THERAPY. - 2018. - Vol.29, Is.12. - P.A122-A122.
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Mingaleeva R. Small molecule MB725: a highly potent modulator of p53(Y220C) mutant / R. Mingaleeva, R. Sayarova, R. Khadiullina, O. Kartseva, I. Glagoleva, N. Alexandrova, A. Hamad, R. Subani, V. Chasov, R. Khairullin, M. Baud, A. Rizvanov, R. Miftakhova, E. Bulatov // Mol. Biol. Cell. – 2018. – P. 2949.
2018_MolBiolCell.pdf -
Valiullina A. Screening for immunosuppressive genes responsible for resistance towards CAR-T cell therapy in cancer cells / A. Valiullina, A. Petukhov, R. Sayarova, M. Zhuravleva, S. Kletukhina, S. Malanin, E. Bulatov, A. Rizvanov // Blood. – 2018. – V.132. – S.1. – P. 4965.
2018_CAR_T_Blood.pdf -
Mingaleeva R.N. Small molecule modulators of mutant p53 and their activity in genetically modified MCF7 cells / R.N. Mingaleeva, R.M. Sayarova, R.R. Nazyrova, M. Baud, A.A. Rizvanov, R.R. Miftakhova, E.R. Bulatov // Abstract book «Kazan precision medicine workshop», Kazan. - 2018. - P. 27.
Precision_medicine_2018.pdf -
Sayarova, R.M. Selective small molecule stabilisers/activators of p53(Y220C) mutant / Regina Sayarova, Raniya Nazyrova, Rimma Mingaleeva, Olga Kartseva, Irina Glagoleva, Natalya Alexandrova, Azzam Hamad, Razan Subani, Vitaly Chasov, Rafil Khairullin, Regina Miftakhova, Matthias Baud, Albert Rizvanov, Emil Bulatov // ECDO – 2018. - P. 45
ECDO2018.pdf -
Valiullina A. Anti-CD19 CAR-T cells are efficient against CD19-positive 3D bioprinted solid tumor models / A. Valiullina, R. Sayarova, A. Petukhov, M. Zhuravleva, E. Bulatov, A. Rizvanov // Human Gene Therapy. – 2018. - A122.
2018_CAR_T__umanGeneTherapy.pdf
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