Article: Selective antimicrobial effects of curcumin @ halloysite nanoformulation: a Caenorhabditis elegans study

Journal: ACS Applied Materials & Interfaces, 10 June 2019, V. 11 (26), P. 23050-23064

Authors: Gölnur Fakhrullina, Elvira Khakimova, Farida Akhatova, Guiseppe Lazzara, Filippo Parisi, Rawil F Fakhrullin

Changes in the normal microbial community of the gastrointestinal tract caused by unhealthy diets, environmental factors and excessive use of antibiotics can seriously affect a person’s health and well-being. The authors have developed new antimicrobial nanocontainers based on the nanotubes of the natural mineral halloysite and hydrophobic curcumin. The treatment of C. elegans nematodes infected with S. marcescens using the obtained nanocontainers completely restored the viability of the nematodes due to the increased bioavailability of hydrophobic curcumin.