Laboratory “Extreme Biology” together with Irkutsk State University, Institute of Biology (Irkutsk, Russia) organized an international seminar entitled “Life of genomes 2015: Mechanisms of Adaptations” in frame of Summer School in Bolshie Koty! The seminar, uniting leading specialists in the field of genomics, evo-devo and computational biology from Russia, Japan and Sweden, touched questions of the modern knowledge of linking of the genome structure and activity to adaptation mechanisms, developmental biology and evolution of organisms and biological molecules. The lectures outlined cutting-edge practical methods in analysis of molecular information and practical approaches in developmental biology.