Research in the "Molecular Immunology" Laboratory focuses on several key areas, such as the regulation of the mTOR1 complex during mitochondrial metabolism: effects on inflammation and carcinogenesis.
The purpose of this project is:
- to study the features of metabolically reprogrammed mitochondria in native, pro-inflammatory and alternatively activated macrophages.
- to determine molecular and functional composition of the hypothetical relationship between mitochondria and the mTORC1 complex.
- to apply the obtained data on mitochondrial adaptation in cancer cells during carcinogenesis in translational medicine.
The methods used: