The Russian Federation patent "PREPARATION FOR SELECTIVE APOPTOTIC ELIMINATION OF TUMOUR CELLS" / Makarov Aleksandr Aleksandrovich (RU), Il'inskaja Ol'ga Nikolaevna (RU), Kolpakov Aleksej Ivanovich (RU), Zelenikhin Pavel Valer'evich (RU), Mit'kevich Vladimir Aleksandrovich (RU), Petrushanko Irina Jur'evna (RU) // Patent 2 567 670.- Date of publication: 10.11.2015 Bull. № 31
SUBSTANCE: invention relates to microbiological industry and can be used in biotechnology, genetic engineering, medicine and veterinary. Claimed is application of RNAase Bacillus sp. VKPM B-9862 as preparation for selective apoptotic elimination of tumour cells. EFFECT: claimed preparation possesses expressed apoptosis-inducing action with respect to malignant cells, without producing toxic effect on normal cells of blood, liver, nervous tissue and fibroblasts.
Kolpakov, A. I.
V.A.Engelgardt award of the Tatarstan Academy of Sciences
for the cycle of works “The change of physiological-biochemical status of the cells under the influence of natural regulators of growth and development”. 30 January 2015.
- In 2015 the Russian Federation patent "The use of Bacillus pumilus ribonuclease as inhibitor of phytopathogenic viruses" / M. R. Sharipova, N. P. Balaban, A. M. Mardanova, A. A. Tojmenceva // Patent 2542480.- Date of publication: 20.02.2015 Bull. No. 5
- Method for producing of inhibitor of phytopathogenic viruses / M. R. Sharipova // know-how No. 082/10/2015 from 30.10.2015.
- In 2013 the Russian Federation patent "The Way of use of Bacillus intermedius ribonuclease" (Kurinenko B. M., Alekseeva I.I. Ilyinskaya O. N.) fixing intellectual property on the introduction of RNase as an antiviral preparation was taken out. The purpose of the invention is to increase the efficiency of suppression of reproduction of viruses in the infected organism, to decrease the specific quantity and the concentration of enzyme needed for suppression of viruses reproduction, to increase the productivity of process of suppression of viruses reproduction, to increase medical effect.
- Since 2011 together with OJSC “Bioenergiya” molecular and genetic methods of the analysis of anaerobic destructors for the purpose of increase of biogas exit on the semi-industrial installation in Buinsk are introduced; the project is supported by the Investment Venture Fund of the Republic of Tatarstan.
- In 2010 together with the Kazan Medical University the design group working on the innovative project "Stomatologic Masseur — New Approach to the Prevention of Stomatologic Diseases", supervised by state non-profit organization "Investment Venture Fund of the Republic of Tatarstan" and the Russian Fund of assistance to the development of small forms of the enterprises in the scientific and technical sphere was created. The project of a new masseur introduction was among residential in Skolkovo.
- Collective work of professors of the department of microbiology O.N. Ilyinskaya, B.M. Kurinenko, M.R. Sharipova "Hydrolase of microorganisms as the potential therapeutic preparations" in 2008 was awarded the State Award of the Republic of Tatarstan in the field of science and technics. The staff of school is indexed as Leading scientific and teaching collective (Them. plan No. 1.4.03).
